Direct Meds GLP-1 vs Enhance MD: Which GLP-1 Provider Is Better?

A side-by-side comparison of Direct Meds GLP-1 and Enhance MD covering pricing, scores, medication types, insurance, and more to help you decide.

Direct Meds GLP-1

#18 of 31
7.9/10

Straightforward compounded GLP-1 program with transparent all-inclusive pricing and no hidden fees.

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Higher Rated

Enhance MD

#8 of 31
8.3/10

Affordable telehealth provider offering both compounded and brand-name GLP-1 medications with combination therapy options.

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FeatureDirect Meds GLP-1Enhance MD
Our Score7.9/108.3/10
Starting Price$280/mo$115/mo
Medication TypeCompoundedBoth
Insurance AcceptedNoNo
Best ForUsers wanting simple, all-inclusive pricing without insuranceBudget-conscious users interested in combination therapies
Ranking#18#8

Pros & Cons Compared

Direct Meds GLP-1

Pros

  • +True all-inclusive pricing — $280/mo covers medication, consultations, shipping, and pharmacy fees with no add-ons
  • +Clear dose-based pricing published on their site — no surprise cost increases when titrating up
  • +Fast pharmacy fulfillment: most orders ship within 48 hours of provider approval
  • +Responsive customer support with live chat available during business hours

Cons

  • Compounded medications only — cannot prescribe brand-name Wegovy, Zepbound, or Ozempic
  • At $280/mo for compounded-only, it's pricier than competitors like Henry Meds ($199) or TrimRx ($179)

Enhance MD

Pros

  • +$115/mo starting price with access to both brand-name and compounded — rare at this price point
  • +Offers combination therapies (GLP-1 + B12, GLP-1 + NAD+) for patients wanting enhanced protocols
  • +Quick asynchronous consultations — most patients approved within 24 hours without video calls
  • +Flexible dosing: can start at lower doses than standard protocols for sensitive patients

Cons

  • Lighter clinical support than higher-priced platforms — check-ins are patient-initiated, not scheduled
  • No insurance billing and limited customer support hours (business days only, no weekends)

Our Verdict

Enhance MD edges out Direct Meds GLP-1 with a score of 8.3/10 vs 7.9/10. If budget is your priority, Enhance MD starts at $115/mo compared to Direct Meds GLP-1's $280/mo. Enhance MD offers both brand-name and compounded medications, giving you more flexibility. Choose Direct Meds GLP-1 if you want: users wanting simple, all-inclusive pricing without insurance. Choose Enhance MD if you want: budget-conscious users interested in combination therapies.

Try Direct Meds GLP-1

Starting at $280/mo

Visit Direct Meds GLP-1

Try Enhance MD

Starting at $115/mo

Visit Enhance MD